Effects of low-molecular-weight heparin and unfractionated heparin on traumatic disseminated intravascular coagulation
نویسندگان
چکیده
منابع مشابه
Unfractionated and low molecular weight heparin
Background Unfractionated heparin (UFH) is mostly obtained from porcine and bovine mucosa and has been widely used for the treatment and prevention of thrombotic events. It consists of molecular chains of various lengths varying from 2000 to 40,000 Da [1]. Low molecular weight heparins (LMWHs) are smaller chains of UFH that can be obtained, from unfractionated heparin, by various chemical and e...
متن کاملCoagulation and Transfusion Medicine / EFFECTS OF LOW-MOLECULAR-WEIGHT HEPARIN AND HEPARINOID ON THROMBOELASTOGRAPHIC ASSAY Effects of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Heparinoid on Thromboelastographic Assay of Blood Coagulation
Thromboelastography (TEG) has been used increasingly as an intraoperative hemostasis monitoring device. Low-molecular-weight heparins are given increasingly to reduce the development of antibodies against the heparin–platelet factor 4 complex, and heparinoids are given to patients who have developed the antibody. We studied the effect of unfractionated heparin, a low-molecular-weight heparin (e...
متن کاملEffect of switching unfractionated heparin to low-molecular-weight heparin on serum potassium in hemodialysis patients.
INTRODUCTION Unfractionated (UF) heparin is the most common anticoagulant used during hemodialysis. Failure of the kidneys to excrete potassium as well as heparin-induced reduction of aldosterone synthesis put hemodialysis patients at risk of hyperkalemia. It has not yet been clearly known whether hyperkalemia is also induced by low-molecular-weight (LMW) heparins. This study aimed to evaluate ...
متن کاملCost-effectiveness of low-molecular-weight heparin and unfractionated heparin in treatment of deep vein thrombosis.
BACKGROUND Acute deep vein thrombosis has traditionally been treated with unfractionated heparin (UFH), administered intravenously, but low-molecular-weight heparins (LMWH), administered subcutaneously, have recently become available. The authors sought to determine which therapy was more cost-effective for inpatient and outpatient treatment of deep vein thrombosis. METHODS An incremental cos...
متن کاملComparison of low-molecular-weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation.
BACKGROUND Low-molecular-weight heparin (LMWH) has been suggested as providing safe, efficient, convenient and possibly more cost-effective anticoagulation for haemodialysis (HD) than unfractionated heparin, with fewer side-effects and possible benefits on uraemic dyslipidaemia. METHODS In this prospective, randomized, cross-over study we compared the safety, clinical efficacy and cost effect...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2018
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v17i5.28